Alzheimer's disease is a neurological disorder in which memory loss and cognitive impairment are caused by the death of brain cells. Alzheimer's disease is a brain disease that affects people of all ages. At first, the symptoms are mild, but as time passes, they become more intense. It was named after Dr. Alois Alzheimer, the first person to identify Alzheimer's disease in 1906. Memory loss, language difficulties, and impulsive or erratic behaviour are all common signs of Alzheimer's disease. Plaques and tangles in the brain are one of the most common symptoms of the disease. A lack of communication between the brain's nerve cells, or neurons, is another symptom. Knowledge cannot easily move between various regions of the brain, or between the brain and muscles or organs, because of these characteristics. People's ability to recall current events, reason, and identify people they know deteriorates as the symptoms worsen. A individual with Alzheimer's disease can eventually need full-time assistance. A neurologist may not be able to tell whether a patient's forgetfulness is due to natural ageing, decreased blood flow to the brain, or, more ominously, Alzheimer's disease. A conclusive Alzheimer's diagnosis could only be made during an autopsy for most of the previous century. Patients can now be diagnosed with Alzheimer's disease even before signs occur, thanks to advances in brain imaging and spinal fluid testing. However, these invasive procedures are costly and, in most cases, confined to research environments, not standard treatment for the millions of people who suffer from the most common neurodegenerative disease. Alzheimer's disease (AD) is the most common form of dementia, and it is marked by cognitive impairment, memory loss, and mood and behaviour changes. While there is still some debate regarding the underlying causes of Alzheimer's disease, one theory known as the amyloid cascade hypothesis is generally accepted. It claims that amyloid-peptides form plaques between neurons over time and set off a chain reaction. It claims that amyloid-peptides build up as plaques between neurons over time, causing a series of pathological events. A42, an amyloid isoform, is a significant component of these amyloid plaques. Since A42 is mixed up in plaques, less A42 is found in the cerebrospinal fluid (CSF) of Alzheimer's patients than in healthy controls. Those who are interested to publish their article in our journal, they can submit it either send it as an email attachment to this below given mail id or submit it online through given link: https://www.longdom.org/submissions/medical-surgical-pathology.html

Media Contact:

John Robert

Journal of Medical and Surgical Pathology

Email: surgpathology@emedsci.com

ISSN: 2472-4971 | NLM ID: 101245791